Mitochondrial mutation associated with hearing loss

Mitochondrial gene mutation screening in hearing loss patients, Hormozgan, Iran

Introduction: Hearing loss is the most frequent sensory disorder occurs in 1/1000 newborns. About 50% of hearing loss cases are due to genetic causes. Mutation in MTRNR1(A1555G), MTTL1(A3243G) and MTTS1(A7445G) are known to be one of the important cause of nonsyndromic Sensorineural hearing loos in some populations. This study aims to demonstrate the frequency of three mitochondrial mutatio...

Is Sudden Hearing Loss Associated with Atherosclerosis?

Introduction: Sudden sensorineural hearing-loss (SSNHL) patients constitute approximately 2–3% of referrals to ear, nose and throat (ENT) clinics. Several predisposing factors have been proposed for this condition; one of which is vascular disorders and perfusion compromise. In this research the atherosclerotic changes and their known risk factors are studied in SSNHL patients.   Materials and ...

Postlingual Hearing Loss as a Mitochondrial 3243A>G Mutation Phenotype

BACKGROUND The prevalence of isolated hearing loss (HL) associated with the m.3243A>G mutation is unknown. The aim of this study was to assess the frequency and heteroplasmy level of the m.3243A>G mutation in a large group of Polish patients with postlingual bilateral sensorineural HL of unidentified cause. METHODOLOGY/PRINCIPAL FINDINGS A molecular search was undertaken in the archival blood...

Hearing Loss and M.1555a>G Mitochondrial Mutation

de Paula, Jorge R. Paschoal, Henrique Furlan Pauna, Tammy Fumiko Messias Takara, Edi Lúcia Sartorato & Guilherme Machado de Carvalho. This is a research/review paper, distributed under the terms of the Creative Commons Attribution-Noncommercial 3.0 Unported License http://creativecommons.org/licenses/by-nc/3.0/), permitting all non-commercial use, distribution, and reproduction in any medium, p...

T mitochondrial dna mutation , hearing loss , and aminoglycosides antibiotics Summary